ChloroquineV1, Main, Exploration, bibRecord, 002620

Current status of artemisinin and its derivatives as antimalarial drugs

Identifieur interne : 002620 ( Main/Exploration ); précédent : 002619; suivant : 002621

Current status of artemisinin and its derivatives as antimalarial drugs

Auteurs : Vikas Dhingra [Inde] ; K. Vishweshwar Rao [Inde] ; M. Lakshmi Narasu [Inde]

Source :

Life Sciences [ 0024-3205 ] ; 1999.

RBID : ISTEX:22A102E8BA7D71E23CD9C9061C851B74A0635730

English descriptors

Teeft :
- Acta, Acton, Annua, Antimalarial, Antimalarial activity, Arteannuin, Arteether, Artemether, Artemisia, Artemisia annua, Artemisinic, Artemisinic acid, Artemisinin, Artemisinin content, Artemisinin derivatives, Artemisinin production, Artemisiu, Artesunate, Assay, Biosynthesis, Biosynthetic, Callus, Chem, Derivative, Dihydroartemisinin, Electrochemical, Ferreira, Hplc, Janick, Jung, Klayman, Lett, Malaria, Malarial, Medica, Meshnick, Nguyen, Parasite, Pathway, Pharmacol, Phytochemistry, Planta, Planta medica, Plasmodium, Pras, Precursor, Sucrose, Suppl, Tran, Trans, Unnuu, Wang, Woerdenbag, Zhou.

Abstract

Abstract: Artemisinin is a promising and a potent antimalarial drug, which meets the dual challenge posed by drug-resistant parasites and rapid progression of malarial illness. This review article focuses on the progress achieved during the last years in the production of artemisinin from Artemisia annua. The structure, biosynthesis and analysis of artemisinin and its mode of action are described. The review also focuses on clinical studies, toxicity studies, pharmcokinetics and activity of artemisinin related compounds. The production strategies including organic synthesis, extraction from plants, in vitro cultures and alternative strategies for enhancing the yields are also discussed.

Url:

https://api.istex.fr/ark:/67375/6H6-W3M9M1DX-B/fulltext.pdf

DOI: 10.1016/S0024-3205(99)00356-2

Affiliations:

Inde

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to stream Istex, to step Corpus: 002405
to stream Istex, to step Curation: 002405
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to stream Main, to step Curation: 002620

Le document en format XML

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<term>Arteannuin</term>
<term>Arteether</term>
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<front><div type="abstract" xml:lang="en">Abstract: Artemisinin is a promising and a potent antimalarial drug, which meets the dual challenge posed by drug-resistant parasites and rapid progression of malarial illness. This review article focuses on the progress achieved during the last years in the production of artemisinin from Artemisia annua. The structure, biosynthesis and analysis of artemisinin and its mode of action are described. The review also focuses on clinical studies, toxicity studies, pharmcokinetics and activity of artemisinin related compounds. The production strategies including organic synthesis, extraction from plants, in vitro cultures and alternative strategies for enhancing the yields are also discussed.</div>
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Current status of artemisinin and its derivatives as antimalarial drugs

Current status of artemisinin and its derivatives as antimalarial drugs

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri